Infectious Disease

With the onset of COVID-19, the Health Innovation Program (HIP) determined they could use the reporting infrastructure they have been developing over the last several years, in partnership with Wisconsin Collaborative for Healthcare Quality (WCHQ), to rapidly produce reports with reliable and accurate data for health systems who are WCHQ members. These reports can help the health systems to prepare for and respond to this pandemic.

The reports provide details on primary care provider panels, clinics, and ZIP codes for each health system and helps the health system to identify the numbers and prevalence of people who are at risk for severe complications from COVID-19.

With the COVID-19 pandemic, UW-Madison researchers within the School of Medicine and Public Health are quickly adapting to support Wisconsin health officials. Researchers at the Health Innovation Program (HIP), who have been working to improve health care using electronic health record data voluntarily provided by over 20 Wisconsin health systems through the Wisconsin Collaborative for Healthcare Quality (WCHQ), have mobilized to determine how they could rapidly use these data to help those on the front line of the battle against COVID-19 to support the direction of efforts towards the places in Wisconsin that need it most.

Because of the COVID-19 pandemic, critically ill patients have been hospitalized and isolated from their families and loved ones. In many hospitals, the palliative care team has been charged with maintaining communication between the critical care team and their patients’ families. Dr. Gretchen Schwarze and her team along with Dr. Toby Campbell created the Best Case/Worst Case: ICU (COVID-19) communication toolkit to assist separated families and to help them develop an understanding of their loved one’s illness, prognostic awareness and the range of possible outcomes.

Predictive analytics has the potential to transform the health care system by using existing data to predict and prevent poor clinical outcomes, provide targeted care, and lower costs. A challenge for health systems is selecting and implementing predictive models within clinical and operational workflows.

To guide health systems through the process of selecting and implementing a predictive model within their system, the UW Health Applied Data Science team and the Health Innovation Program developed a toolkit to support planning for and implementation of a predictive model. This toolkit was tested through the implementation of a sepsis prediction model in the inpatient setting at UW Health, a large Midwestern academic health system with four hospitals.

Healthcare-associated infections (HAIs) are an issue of public health importance, as approximately 722,000 people are afflicted by an HAI every year (1 in 25 hospitalized patients) and 75,000 people with HAIs die. Daily bathing treatments with chlorhexidine gluconate (CHG) for hospitalized patients is one evidence-based intervention targeting HAIs. However, it is often challenging to implement these daily bathing treatments widely across an organization.

HIP Investigators Meghan Brennan, MD and Heidi Brown, MD were recently awarded pilot funding through the University of Wisconsin - Madison Institute for Clinical and Translational Research (UW ICTR).  

Nasia Safdar has been awarded a contract from the Patient-Centered Outcomes Research Institute (PCORI) to improve research on the prevention and treatment of healthcare-associated infections (HAI). Dr. Safdar’s project creates a sustainable panel of older rural Wisconsin patients and their families, and other stakeholders including UW Health Infection Prevention staff and the Wisconsin Division of Public Health. To achieve this goal, Dr. Safdar and Researcher Mary Jo Knobloch will collaborate with Dr.

Dr. Chris Crnich was recently awarded a 3-year R18 grant from the Agency for Healthcare Research and Quality (AHRQ) for his project, "Building a novel antibiotic stewardship intervention for nursing homes." The objectives of this project are to develop and evaluate a complex intervention to reduce inappropriate antibiotic use in nursing homes.

Dr. Nasia Safdar recently won the John Q. Sherman Award for Excellence in Patient Engagement. This award recognizes individuals and healthcare provider institutions that are changing the face of healthcare by using innovative programs and approaches that increase patient and family engagement.

Read more about the award and Dr. Safdar's innovative approach to involving patients in reducing infections at EngagingPatients.org.